Antipyretic Effect of Acetaminophen Versus Ibuprofen in Children Referred to the Pediatric Clinic of Imam Reza Hospital (Mashhad)

Authors

  • Ghodsi, Alireza
  • Hamedi, Abdolkarim
  • Kouzegaran, Samaneh
Abstract:

Introduction: Acetaminophen and ibuprofen are the most widely used drugs in pediatric medicine to control fever and pain. There are different opinions about the effectiveness, duration of effects, and side effects and duration of action in controlling pain and fever of these drugs. In this study, we decided to examine the antipyretic effects of two common drugs to provide solutions based on the results. Methods: During six months in the second half of the year, 400 children referred to a pediatric clinic with fever were divided into two groups. One group was prescribed acetaminophen at a dose of 15 mg per kg every 4 to 6 hours to control fever, and the other group was prescribed ibuprofen at a dose of 10 mg per kg every 6 to 8 hours. Patients underwent telephone or in-person follow-up 24 hours after drug administration, and each group was evaluated for the time to stop fever after medication, the duration without the fever after each dose, and the interval between doses. Results: Four hundred children were examined and split into 185 children in the first group (acetaminophen) and 145 children in the second group (ibuprofen). In the first group, the average duration of stop the fever after taking the drug was 35 minutes, and in the second group, 55 minutes. Duration without fever after taking the drug was 2 hours in the first group and 4 hours in the second group. In the first group, drug dissatisfaction was much lower than in the second group. Conclusions: The best antipyretic drug in children, especially in infections, is acetaminophen, which, of course, must be taken in sufficient and correct doses and avoid taking antipyretic drugs, which is also anti-inflammatory. Although ibuprofen and diclofenac are also antipyretics, they should not be used as antipyretics, especially in pediatric infections. Compared to acetaminophen, these drugs have both more side effects and a longer reduction in body temperature.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

A Retrospective Study of Ectoparasitosis in Patients Referred to Imam Reza Hospital of Mashhad, Iran

This cross-sectional study was performed on all patients suspected to be suffering from ectoparasites who were referred to the parasitology laboratory of Imam Reza Hospital of Mashhad during 15 years (April 1995 to April 2010). All patients' data were collected from the questionnaires and then analyzed statistically. From 1814 suspected patients to be suffering from ectoparasites, 375 patients ...

full text

Clinical and Epidemiological Evaluation of Patients with Anogenital Warts Referred to Dermatology Clinic of Imam-Reza Hospital in Mashhad

Introduction: Genital infections with human papilloma virus (HPV) are the most common sexually transmitted disease in the United States. Several predisposing factors are known for this infection. So far, no studies on the risk factors and clinico-epidemiologic aspects of genital warts in Iran have been reported. So, we performed this study to evaluate epidemiologic aspects of anogenital warts i...

full text

A retrospective study of cutaneous fungal infections in patients referred to Imam Reza Hospital of Mashhad, Iran during 2000-2011

BACKGROUND AND PURPOSE Detection of agents responsible for cutaneous mycosis may be effective in the prevention of fungal infections from environmental and animal sources. With this background in mind, in this study, we aimed to identify the distribution of cutaneous mycotic infections in patients referred to Imam Reza Hospital of Mashhad, Iran during 2000- 2011. MATERIALS AND METHODS In tota...

full text

Seroepidemiology of Toxocariasis in Children (5–15 yr Old) Referred to the Pediatric Clinic of Imam Hossein Hospital, Isfahan, Iran

BACKGROUND Human toxocariasis, a helminthozoonosis, is due to the migration of Toxocara species larvae into human organisms. Humans, especially children become infected by ingesting of embryonated eggs from soil, dirty hands, and raw vegetables. Seroprevalence of this infection is high in developed countries, especially in rural areas. The aim of this study was to investigate the seroepidemiolo...

full text

The incidence of cross infections in Imam Reza hospital, Mashhad, Iran

BACKGROUND AND OBJECTIVES Cross Infections (CIs) are considered as a major public health problem worldwide. They cause delay in recovery, increased mortality and morbidity. The purpose of this study is to report the incidence of CIs in our teaching hospital during a 23-month period. MATERIALS AND METHODS In this descriptive cross-sectional study, 76766 patients from 2009 to 2011 admitted to 1...

full text

Antipyretic efficacy of acetaminophen and ibuprofen in children aged 6 months to 10 years

Introduction: Fever and consequent convulsion are among major concerns for parents of febrile children. Many antipyretic drugs are applied excessively to decrease fever in children. This research is designed to study the efficacy and stability effects of cetaminophen and Ibuprofen in febrile children aged 6 months to 10 years old. Methods: This single-blind clinical trial study was performed o...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 12  issue 2

pages  70- 74

publication date 2020-10

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

No Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023